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Chiral Analysis

ISBN-10:0-44451669-7
ISBN-13:978-0-44451669-5

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Description

General descriptionChiral Analysis covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals. The target audience is scientific professionals with an undergraduate background in chemistry or a related discipline, specifically organic chemists, researchers in drug discovery, pharmaceutical researchers involved with process analysis or combinatorial libraries, and graduate students in chemistry. Chapters have been written with the nonspecialist in mind so as to be self-contained

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publication infoK. Busch and M. Busch, ed., Elsevier Science, 2006, 720 pp., hard cover

Table Of Contents

Table of ContentsPART I
Chapter 1. A History of Chirality
Chapter 2: Chiral Asymmetry in Nature
Chapter 3. Physical Properties and Enantiomeric Composition
Chapter 4. Emerging High-Throughput Screening Methods for Asymmetric Induction .
PART II
Chapter 5. Analysis of Chiral Chromatographic Separations by Molecular Modeling
Chapter 6. Gas chromatographic enantioseparation of chiral pollutants – Techniques and Results
Chapter 7. HPLC Resolution Using Polysaccharide Derivatives as CSPs
Chapter 8. Chiral Separations by Capillary Electrophoresis
Chapter 9. Chiral Separations in Microfluidic Devices
PART III
Chapter 10. Instrumental Aspects of Chiroptical Detection
Chapter 11. Micro-Scale Polarimetry .
Chapter 12. Chiral Analysis by Regression Modeling of Spectral Data
Chapter 13. Electronic Circular Dichroism for Chiral Analysis
Chapter 14. Determination of Molecular Stereochemistry using Optical Rotatory Dispersion, Vibrational Circular Dichroism and Vibrational Raman Optical Activity
Chapter 15. Vibrational Optical Activity in Chiral Analysis
Chapter 16. Raman Optical Activity
Chapter 17 Mass Spectral Methods of Chiral Analysis
Chapter 18 Novel Chiral Derivatizing Agents Powerful for Enantioresolution and Determination of Absolute Stereochemistry by X-Ray Crystallographic and 1H NMR Anisotropy Methods